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- 2025年10月16日
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| 产品编号 | bs-41609P |
| 英文名称 | Human Prostate Specific Antigen protein |
| 中文名称 | 人前列腺特异性抗原（天然蛋白） |
| 英文别名 | PSA; Native Human Prostate Specific Antigen protein; Prostate Specific Antigen, Native; |
| 性状 | Lyophilized |
| 理论分子量 | 34 |
| 研究领域 | Cancer > Tumor biomarkers > Tumor antigens Cancer > Tumor immunology > Tumor-associated antigens Neuroscience > Cell Adhesion Proteins > Proteases Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > Kallikreins Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚基 | Forms heterodimer with SERPINA5. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Prostate. |
| 翻译后修饰 | Belongs to the peptidase S1 family. Kallikrein subfamily. Contains 1 peptidase S1 domain. |
| 相似性 | Belongs to the peptidase S1 family. Kallikrein subfamily. Contains 1 peptidase S1 domain. |
| 功能 | Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. |
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文献和实验[IF={{ 8.008 }}] {Li Fu. et al. A General Route for Chemiluminescence of n-Type Au Nanocrystals. ANAL CHEM. 2022;94(24):8811–8817} {Other} {}
[IF={{ 8.008 }}] {Yuqi Xu. et al. Surface Defect-Involved and Single-Color Electrochemiluminescence of Gold Nanoclusters for Immunoassay. ANAL CHEM. 2022;94(35):12070–12077} {Other} {Other}
[IF={{ 8.008 }}] {Li Fu. et al. Coreactant-free and Near-Infrared Electrochemiluminescence Immunoassay with n-Type Au Nanocrystals as Luminophores. ANAL CHEM. 2022;94(34):11934–11939} {Other} {Other}
[IF={{ 8.008 }}] {Xuwen Gao. et al. Spectrum-Resolved Electrochemiluminescence to Multiplex the Immunoassay and DNA Probe Assay. ANAL CHEM. 2022;XXXX(XXX):XXX-XXX} {Other} {}
[IF={{ 8.008 }}] {Xuwen Gao. et al. Luminophore-Surface-Engineering-Enabled Low-Triggering-Potential and Coreactant-Free Electrochemiluminescence for Protein Determination. ANAL CHEM. 2023;95(17):6948–6954} {Other} {}
Synthesis of a Virus Electrode for Measurement of Prostate Specific Membrane Antigen
. The methods described here utilize electrochemical impedance spectroscopy (EIS) to detect molecular recognition between M13 phage bound to a Au electrode and the following analytes: prostate specific membrane antigen (PSMA), positive and negative control
Antigen-Specific Human Monoclonal Antibodies from Transgenic Mice
the expression of mouse heavy or light chains, the endogenous mouse Ig (mIg) loci must be silenced by gene-targeting techniques. Subsequently, to obtain antigen-specific mAbs, conventional immunization protocols can be followed and the mAb technique used (fusion
Generation and Cloning of Antigen-Specific Human T-Cells
in the presence of TCGF-containing supernatant only, long-term cultures of cloned human allo-antigen-specific T-cell lines (3 , 4 ) needed repetitive stimulation with specific allo-antigen for then growth (3 ) This led to the general assumption that antigen
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