rHu NLRP3 | NALP3/Cryopyrin Protein, His(bs-41295P)-20ug/100ug/500ug产品图

rHu NLRP3 | NALP3/Cryopyrin Pr

otein, His(bs-41295P)-20ug/100ug/500ug
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  • ¥580 - 5680
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  • bs-41295P
  • 2026年10月10日
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      20ug/100ug/500ug

    规格:20ug产品价格:¥580.0
    规格:100ug产品价格:¥1880.0
    规格:500ug产品价格:¥5680.0
    产品编号bs-41295P
    英文名称Recombinant human NALP3 protein, His
    中文名称重组人NALP3蛋白
    英文别名LRR and PYD domains-containing protein 3; AGTAVPRL; AII/AVP antibody Angiotensin/vasopressin receptor AII/AVP like; Angiotensin/vasopressin receptor AII/AVP-like; C1orf7; Caterpiller protein 1.1; CIAS 1; CIAS1; CLR1.1; Cold autoinflammatory syndrome 1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; Familial cold autoinflammatory syndrome; FCAS; FCU; Muckle-Wells syndrome; MWS; NACHT; NACHT LRR and PYD containing protein 3; NALP 3; NALP3; NALP3_HUMAN; NLRP3; PYPAF 1; PYPAF1 antibody PYRIN containing APAF1 like protein 1; PYRIN-containing APAF1-like protein 1; Recombinant human NALP3 protein, His
    性状Lyophilized or Liqui
    纯化方法AC
    理论分子量21.9
    实际分子量23 kDa
    浓度>0.5 mg/ml
    储存液20mM Tris-HCl (pH8.0).
    研究领域

    Cancer > Growth factors > TNF

    Cardiovascular > Atherosclerosis > Vascular Inflammation > Inflammatory mediators

    Immunology > Innate Immunity > Macrophage / Inflamm.

    Signal Transduction > Signaling Pathway > Nuclear Signaling > NFkB Pathway

    亚细胞定位Cytoplasm.
    组织特异性Expressed in blood leukocytes. Strongly expressed in polymorphonuclear cells and osteoblasts. Undetectable or expressed at a lower magnitude in B- and T-lymphoblasts, respectively. High level of expression detected in chondrocytes. Detected in non-keratinizing epithelia of oropharynx, esophagus and ectocervix and in the urothelial layer of the bladder.
    相似性Belongs to the NLRP family.
    Contains 1 DAPIN domain.
    Contains 9 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
    功能May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
    保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.Subcellular Location : Cytoplasm.

     

     

    产品细节图片1
    The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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    rHu NLRP3 | NALP3/Cryopyrin Protein, His(bs-41295P)-20ug/100ug/500ug
    ¥580 - 5680