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500ug
| 产品编号 | bs-12050P |
| 英文名称 | HTR2B Antibody Blocking Peptide |
| 中文名称 | 5-羟色胺受体2B封闭多肽 |
| 英文别名 | SR-2B; 5 HT 2B; 5 HT 2B receptor; 5 HT(2B); 5 HT2B; 5 hydroxytryptamine (serotonin) receptor 2B; 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled; 5 hydroxytryptamine 2B receptor; 5 hydroxytryptamine receptor 2B; 5-HT-2B; 5-HT2B; 5-hydroxytryptamine receptor 2B; 5HT(2B); 5HT2B_HUMAN; 5HT2F; Htr 2b; Htr2b; NP75 protein; SEROTONIN 5HT2B RECEPTOR; Serotonin receptor 2B; Stomach fundus serotonin receptor. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Types of disease > Obesity Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Serotonin Receptors |
| 亚基 | Interacts with MPDZ. |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Expressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.[supplied by OMIM]. |
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文献和实验Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
Adey, N.B., Mataragonon, A.H., Rider, J.E., Carter, J.M., and Kay, B.K. 1995. Characterization of phage that bind plastic from phage‐displayed random peptide libraries. Gene 156:27‐31
自体活性物质（autacoids）又称局部激素，多数是机体受到伤害性刺激后产生，以旁分泌方式到达邻近部位发挥作用。它们在局部合成后，不进入血液循环，主要在合成部位附近发挥作用，且半衰期短暂。组胺（histamine）、前列腺素（prostaglandin, PG）、白三烯（leukotriene）、5-羟色胺（5-HTA）和血管活性肽类（vasoactive peptide）、P物质（substance P）、激肽类（kinins）、血管紧张素（angiotensin
【申请上传】Current Protocols in Immunology
9.1 Introduction to Peptide Synthesis Unit 9.2 Synthetic Peptides for Production of Antibodies that Recognize Intact Proteins Unit 9.3 Production of Anti-Peptide Antisera Unit 9.4 B Cell Epitope Mapping Using Synthetic Peptides Unit 9.5 Identification of B Cell
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