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| 产品编号 | bs-1204P |
| 英文名称 | P2Y1 receptor Antibody Blocking Peptide |
| 中文名称 | P2Y1受体封闭多肽/嘌呤受体封闭多肽 |
| 英文别名 | ATP receptor; P2 purinoceptor subtype Y1; P2RY1; P2Y purinoceptor 1; P2Y1 purinoceptor; Platelet ADP receptor; Purinergic receptor; Purinergic receptor P2Y G protein coupled 1; Purinergic receptor P2Y1; P2RY1_HUMAN; P2Y1 purinoceptor. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in muscle, heart, liver, kidney, lung, brain, spleen, but not in testis. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008] |
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文献和实验Blocking of unwanted non-specific staining
and other cell types. By exploiting the preferential avidity of Fc receptor for human > mouse Ig> rabbit > swine > goat immunoglubulins, one may use a blocking of the receptors with a reagent which will not interfere with the secondary reagents
Peptide Microarrays on Coated Silicon Slides for Highly Sensitive Antibody Detection
Peptides, with their well-established chemistry and fully automated synthesis, provide an invaluable tool for the screening of protein ligands, for epitope mapping, and for antibody diagnostics on the microarray format. The method
Aspects of CNS Lupus: Mouse Models of Anti-NMDA Receptor Antibody Mediated Reactivity
transfer of pathology by injecting human and mouse brain-reactive antibodies into adult mouse as well as injecting the antibody into gestating mice and transfer of antibody from dam to fetus, (5) blocking NMDAR-mediated pathogenicity in vivo, (6) evacuation
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