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500ug
| 产品编号 | bs-2799P |
| 英文名称 | DEFA4 Antibody Blocking Peptide |
| 中文名称 | 防御素α4封闭多肽 |
| 英文别名 | Neutrophil defensin 4; Corticostatin; Defensin alpha 4; Defensin, alpha 4; HNP-4; HP-4; HNP 4; defensin, alpha 4, corticostatin; neutrophil defensin 4 precursor; neutrophil defensin 4 preproprotein; DEF4; DEFA4; DEF4_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Adaptive Immunity > T Cells > Non-CD Microbiology > Antimicrobial > Antibiotic Microbiology > Interspecies Interaction > Host Immune Response |
| 亚基 | Homodimer. |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the alpha-defensin family. |
| 功能 | Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq]. |
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DEFA4 Antibody Blocking Peptide(bs-2799P)-500ug
¥880







