DEFA4 Antibody Blocking Peptide(bs-2799P)-500ug

DEFA4 Antibody Blocking Peptid

e(bs-2799P)-500ug
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  • ¥880
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  • bs-2799P
  • 2025年10月16日
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      500ug

    产品编号bs-2799P
    英文名称DEFA4 Antibody Blocking Peptide
    中文名称防御素α4封闭多肽
    英文别名Neutrophil defensin 4; Corticostatin; Defensin alpha 4; Defensin, alpha 4; HNP-4; HP-4; HNP 4; defensin, alpha 4, corticostatin; neutrophil defensin 4 precursor; neutrophil defensin 4 preproprotein; DEF4; DEFA4; DEF4_HUMAN.
    纯化方法HPLC
    研究领域

    Immunology > Adaptive Immunity > T Cells > Non-CD

    Microbiology > Antimicrobial > Antibiotic

    Microbiology > Interspecies Interaction > Host Immune Response

    亚基Homodimer.
    亚细胞定位Secreted.
    相似性Belongs to the alpha-defensin family.
    功能Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq].

     

     

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