SBF1 | MTMR5 Ab Blocking Peptide(bs-17248P)-500ug产品图

SBF1 | MTMR5 Ab Blocking Pepti

de(bs-17248P)-500ug
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  • bs-17248P
  • 2026年10月10日
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    • 规格:

      500ug

    产品编号bs-17248P
    英文名称SBF1 Antibody Blocking Peptide
    中文名称肌微管蛋白MTMR5封闭多肽
    英文别名SBF1; C22:RP4-579N16.2; CMT4B3; MTMR5_HUMAN; DENN/MADD domain containing 7A; DENND7A; MTMR5; Myotubularin related 5; Myotubularin-related protein 5; SET-binding factor 1.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Phosphorylation > Tyrosine Phosphatases

    亚基Interacts with the SET domain of KMT2A/MLL1. Interacts with SUV39H1.
    亚细胞定位Nuclear
    相似性Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
    Contains 1 dDENN domain.
    Contains 1 DENN domain.
    Contains 1 GRAM domain.
    Contains 1 myotubularin phosphatase domain.
    Contains 1 PH domain.
    Contains 1 uDENN domain._x000D_
    功能Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts. According to PubMed:20937701, may function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts. May function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.

     

     

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