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- 详细信息
- 技术资料
- 规格:
500ug
| 产品编号 | bs-11549P |
| 英文名称 | DISP1 Antibody Blocking Peptide |
| 中文名称 | 膜转运蛋白DISPA封闭多肽 |
| 英文别名 | DISP1; DISP 1; disp1; DISP1_HUMAN; DISPA; Dispatched A; Dispatched homolog 1; DKFZP434I0428; FLJ43740; MGC104180; MGC13130; MGC16796; Protein dispatched homolog 1. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neural Signal Transduction |
| 亚细胞定位 | Membrane; Multi-pass membrane protein |
| 相似性 | Belongs to the dispatched family. Contains 1 SSD (sterol-sensing) domain. |
| 功能 | Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008] |
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DISP1 Antibody Blocking Peptide(bs-11549P)-500ug
¥880





