DISP1 Antibody Blocking Peptide(bs-11549P)-500ug

DISP1 Antibody Blocking Peptid

e(bs-11549P)-500ug
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  • bs-11549P
  • 2025年10月16日
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      500ug

    产品编号bs-11549P
    英文名称DISP1 Antibody Blocking Peptide
    中文名称膜转运蛋白DISPA封闭多肽
    英文别名DISP1; DISP 1; disp1; DISP1_HUMAN; DISPA; Dispatched A; Dispatched homolog 1; DKFZP434I0428; FLJ43740; MGC104180; MGC13130; MGC16796; Protein dispatched homolog 1.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurology process > Neural Signal Transduction

    亚细胞定位Membrane; Multi-pass membrane protein
    相似性Belongs to the dispatched family.
    Contains 1 SSD (sterol-sensing) domain.
    功能Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008]

     

     

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