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- bs-3660P
- 2026年10月10日
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| 产品编号 | bs-3660P |
| 英文名称 | srGAP3 Antibody Blocking Peptide |
| 中文名称 | 精神障碍相关GAP蛋白封闭多肽 |
| 英文别名 | ARHGAP 14; ARHGAP14; Gbi; ME GAP; MEGAP; Mental disorder associated GAP; Rho GTPase activating protein 14; SLIT ROBO Rho GTPase activating protein 3; srGAP 2; srGAP 3; srGAP2; SRGP 2; SRGP2; WAVE associated Rac GTPase activating protein; WRP. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neural Signal Transduction Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Regulators |
| 亚基 | Interacts with WASF1. Probably interacts with ROBO1. Interacts with FASLG. |
| 组织特异性 | Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | srGAP3 (SLIT ROBO Rho GTPase-activating protein 3) is a GTPase activating protein (GAP) for the small G protein Rac. It has a putative role in attenuating Rac1 signalling in neurons. srGAP3 is thought to act downstream of the Slit-Robo pathway, which regulates neuronal migration and axonal branching, and play an important role in axonal regeneration after axotomy. It also plays a putative role in severe mental retardation. |
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文献和实验Dual-Color ELISPOT Assay for the Simultaneous Detection of IL-2 and/or IFN- Secreting T Cells
, activate AEC buffer using H2 O2 (see Step 25). Anti-CD3 monoclonal antibody (mAb) (Fisher Scientific) Blocking buffer for ELISPOT assay CEF peptide pool (available from the NIH AIDS Research and Reagent Program and other commercial
0.3% hydrogen peroxide (prepare immediately before use) Blocking buffer (see recipe ) HCV‐specific primary antibody (Ab), e.g
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