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- Bioss
- bs-16315P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16315P |
| 英文名称 | GRID2 Antibody Blocking Peptide |
| 中文名称 | 谷氨酸受体亚基δ2/GluR-δ2封闭多肽 |
| 英文别名 | GLUR D2; GluR delta 2; GLURD 2; GRID2_HUMAN; GLURD2; Glutamate receptor delta 2 subunit; Glutamate receptor ionotropic delta 2; GRID 2; MGC117022; MGC117023; MGC117024. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > More Channels Neuroscience > Neurotransmitter > Amino Acids > Glutamate |
| 亚基 | Interacts with AIP1, AP4M1, BECN1, GOPC, GRID2IP, SHANK1 and SHANK2 (By similarity). |
| 亚细胞定位 | Mitochondrial |
| 相似性 | Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRID2 subfamily. |
| 功能 | GLUD2, Glutamate dehydrogenase 2, is important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission. It is expressed in retina, testis and, at a lower level, brain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain. |
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GRID2 Antibody Blocking Peptide(bs-16315P)-500ug
￥880
