- ￥880
- Bioss
- bs-17481P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-17481P |
| 英文名称 | SIAH3 Antibody Blocking Peptide |
| 中文名称 | SIAH3蛋白封闭多肽 |
| 英文别名 | FLJ39203; Gm912; RP11-480G1.1; Seven in absentia homolog 3; Siah-3; SIAH3; SIAH3_HUMAN. |
| 纯化方法 | HPLC |
| 相似性 | Belongs to the SINA (Seven in absentia) family. Contains 1 SIAH-type zinc finger. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Members of the SINA (seven in absentia) protein family are components of ubiquitin ligase complexes, which target proteins for proteasomal degradation. SIAH3 (seven in absentia homolog 3) is a 269 amino acid protein that belongs to the SINA family, contains one SIAH-type zinc finger and is encoded by a gene located on human chromosome 13. Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. |
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SIAH3 Antibody Blocking Peptide(bs-17481P)-500ug
￥880
