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- TD-HYP0198
- 2025年10月15日
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- 技术资料
- 库存：
88
- 规格：
20mg
| Product Name | Neuropeptide Y (human,rat,mouse) (Synonyms: Neuropeptide Y (29-64), amide) |
| Cat. No. | TD-HYP0198 |
| Description | Neuropeptide Y (human,rat,mouse) 和阿尔兹海默症相关，能够保护老鼠皮质神经元对抗淀粉样蛋白毒性。 |
| Purity | 99.94% |
| CAS No. | 90880-35-6 |
| 分子式 | C₁₈₉H₂₈₅N₅₅O₅₇S |
| 分子量 | 4271.68 |
| Sequence | Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH₂ |
| Sequence Shortening | YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH₂ |
| 作用靶点 | Neuropeptide Y Receptor |
| 作用通路 | GPCR/G Protein; Neuronal Signaling |
| 储存方式 | Sealed storage, away from moisture and light Powder：-80°C, 2 years; -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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文献和实验Characterization of Neuropeptide Y (NPY) Receptors
.A., and Weinshank, R.L. 1995. Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y and peptide YY. J. Biol. Chem. 270:26762‐26765.
Human Type 2 Neuropeptide Y Receptor Gene: Isolation and Characterization
two and seven (1 ). One of the sequences identified encoded the partial sequence of a novel protein most closely related to the type 1 neuropeptide Y (NPY) receptor, the only member of the NPY receptor family characterized by molecular cloning at that time
(2 ). This receptor is PYY preferring since it binds the intestinal hormone PYY (3 ) with high affinity and neuropeptide Y (NPY) (3 ) with a 5–10-fold lower affinity (1 –3 ). PYY and NPY trigger several biological effects through interaction with PYY receptors
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