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- IHC0593H
- 2025年10月15日
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50T
| 产品编号 | IHC0593H |
| 英文名称 | Human Cytokeratin 16 Ready-To-Use IHC Kit |
| 中文名称 | 人细胞角蛋白16即用型免疫组化试剂盒 |
| 英文别名 | CK16; FNEPPK; K16; K1CP; KRT16; KRT16A; NEPPK; PC1 |
| 产品应用 | IHC-P Not yet tested in other applications. |
| 交叉反应 | Human |
| 亚基 | Heterodimer of a type I and a type II keratin. KRT16 associates with KRT6 isomers (KRT6A or KRT6B) (By similarity). Interacts with TCHP (PubMed:15731013). Interacts with TRADD (By similarity). |
| 亚细胞定位 | #Intermediate filament #Keratin |
| 组织特异性 | Expressed in the corneal epithelium (at protein level). |
| 相似性 | Belongs to the intermediate filament family. |
| 功能 | Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 背景资料 | KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. |
| 应用 | 推荐稀释比例 |
Immunohistochemical analysis of paraffin embedded Human tonsil tissue slide using IHC0593H (Human Cytokeratin 16 Kit).
Immunohistochemical analysis of paraffin embedded Human abdominal skin tissue slide using IHC0593H (Human Cytokeratin 16 Kit).
Immunohistochemical analysis of paraffin embedded Human skeletal muscle tissue slide using IHC0593H (Human Cytokeratin 16 Kit).
Immunohistochemical analysis of paraffin embedded Human esophagus tissue slide using IHC0593H (Human Cytokeratin 16 Kit).
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Human Cytokeratin 16 Ready-To-Use IHC Kit(IHC0593H)-50T
￥3200
