- ￥3200
- Bioss
- IHC0276H
- 2025年10月15日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
50T
| 产品编号 | IHC0276H |
| 英文名称 | Human BOB1 Ready-To-Use IHC Kit |
| 中文名称 | 人B细胞特异性转录因子OBF-1即用型免疫组化试剂盒 |
| 英文别名 | BOB1; OBF-1; OBF1; OCAB; POU2AF1; B cell Oct binding protein 1; B cell specific coactivator OBF 1; B cell specific coactivator OBF1; B-cell-specific coactivator OBF-1; BOB 1; BOB-1; OBF 1; OBF1_HUMAN; OCA B; OCA-B; OCT binding factor 1; OCT-binding factor 1; POU class 2 associating factor 1; POU domain class 2 associating factor 1; POU domain class 2-associating factor 1; Pou2af1 |
| 产品应用 | IHC-P Not yet tested in other applications. |
| 交叉反应 | Human |
| 亚基 | Interacts with POU2F1/OCT1 and POU2F2/OCT2; the interaction increases POU2F1 and POU2F2 transactivation activity. |
| 亚细胞定位 | Nucleus |
| 组织特异性 | B-cell specific (PubMed:7779176, PubMed:7859290). Detected in mainly in spleen, but also in thymus, periphral blood leukocyte and small intestine (PubMed:7779176, PubMed:7859290). |
| 翻译后修饰 | Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. |
| 相似性 | Belongs to the POU2AF family. |
| 功能 | Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2 (PubMed:7859290). It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2 (PubMed:7779176). It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2 (PubMed:7779176). It is essential for the response of B-cells to antigens and required for the formation of germinal centers (PubMed:7623806, PubMed:7859290). Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator (By similarity). |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. |
| 应用 | 推荐稀释比例 |
Immunohistochemical analysis of paraffin embedded human tonsil tissue slide using IHC0276H (Human BOB1 IHC Kit).
Immunohistochemical analysis of paraffin embedded human spleen tissue slide using IHC0276H (Human BOB1 IHC Kit).
Immunohistochemical analysis of paraffin embedded human esophageal cancer tissue slide using IHC0276H (Human BOB1 IHC Kit).
Immunohistochemical analysis of paraffin embedded human gastric cancer tissue slide using IHC0276H (Human BOB1 IHC Kit).
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
Human BOB1 Ready-To-Use IHC Kit(IHC0276H)-50T
￥3200
