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- IHC0232H
- 2025年10月15日
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50T
| 产品编号 | IHC0232H |
| 英文名称 | Human CD1A Ready-To-Use IHC Kit |
| 中文名称 | 人T淋巴细胞CD1即用型免疫组化试剂盒 |
| 英文别名 | CD1; CD1A; FCB6; HTA1; R4; T6; CD 1a; CD1A Antigen; CD1A antigen; a polypeptide; CD1a molecule; CD1A_HUMAN; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1 alpha 3; epidermal dendritic cell marker CD1a; FCB 6; HTA 1; hTa1 thymocyte antigen |
| 产品应用 | IHC-P Not yet tested in other applications. |
| 交叉反应 | Human |
| 亚基 | Heterodimer with B2M (beta-2-microglobulin). Interacts with CD74. |
| 亚细胞定位 | Cell membrane Endosome Membrane |
| 组织特异性 | Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. |
| 功能 | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta 2 microglobulin. CD1a is expressed by cortical thymocytes, Langerhan's cells and by interdigitating cells. CD1a is also expressed by some malignancies of T cell lineage and in histiocytosis X. CD1a is expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. CD1a is structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. CD1a localizes to the plasma membrane and recycles vesicles of the early endocytic system. At least five CD1 genes (CD1a, b, c, d, and e) are identified. Alternatively spliced transcript variants of CD1a have been observed, but their biological validity have not been determined. |
| 应用 | 推荐稀释比例 |
Immunohistochemical analysis of paraffin embedded human tonsil tissue slide using IHC0232H (Human CD1A IHC Kit).
Immunohistochemical analysis of paraffin embedded human skin tissue slide using IHC0232H (Human CD1A IHC Kit).
Immunohistochemical analysis of paraffin embedded human esophagus tissue slide using IHC0232H (Human CD1A IHC Kit).
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Human CD1A Ready-To-Use IHC Kit(IHC0232H)-50T
￥3200
