- ￥2719 - 6741
- Bioss
- D57790
- 2025年10月17日
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- 详细信息
- 技术资料
- 规格：
1mg/5mg
| 规格： | 1mg | 产品价格： | ￥2719.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥6741.0 |
| 产品编号 | D57790 |
| 英文名称 | Crebinostat |
| 理论分子量 | 353.41 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Crebinostat is a potent histone deacetylase (HDAC) inhibitor, inhibiting HDAC1, HDAC2, HDAC3, and HDAC6 with IC50s of 0.7 nM, 1.0 nM, 2.0 nM, and 9.3 nM, respectively.Crebinostat increases the density of synapsin-1 punctae along dendrites in neurons in vitro. Crebinostat increased the density of synapsin-1 punctae along dendrites in neurons in vitro. crebinostat modulated chromatin-mediated neuroplasticity and enhanced memory in mice. crebinostat induced histone H3 and histone H4 acetylation and enhanced the expression of the cAMP-responsive element binding protein (CREB) target gene, Egr1. Crebinostat induces histone H3 and histone H4 acetylation and enhances the expression of Egr1, a cAMP response element binding protein (CREB) target. |
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Crebinostat(D57790)-1mg/5mg
￥2719 - 6741
