- ￥625 - 1713
- Bioss
- D55205
- 2025年10月17日
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- 规格：
1mg/1mL x 10mM (in DMSO)
| 规格： | 1mg | 产品价格： | ￥625.0 |
|---|---|---|---|
| 规格： | 1mL x 10mM (in DMSO) | 产品价格： | ￥1713.0 |
| 产品编号 | D55205 |
| 英文名称 | ML266 |
| 理论分子量 | 496.35 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ML266 is glucocerebrosidase (GCase) molecule chaperone, IC50 = 2.5 µM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease. |
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文献和实验Clonality - X Chromosome Inactivation Assay
can utilize X chromosome inactivation (methylation) to determine the clonality status of a tumor or premalignant lesion in females. The technique is based on a methylation-sensitive restriction enzyme and analysis of a polymorphic locus on the X chromosome
the gel: dissolve 0.8g agarose in 100mL of 10mM NaPO4 pH 7.0 (5mL of 0.2M NaP04 pH 7.0 + 95mL "DEPC" H2 O). Make sure gel box and comb are RNase-free by treatment with 3% H2 O2 or commericial RNase removal product (e.g. RNase Zap from Ambion).
Methods for the Detection of D-Amino-Acid Oxidase
were homogenized in 7 mM pyrophosphate buffer (pH 8.3). The homogenates were centrifuged at 550 x g for 5 minutes. The supernatant solutions were used for the assay. The reaction mixture consisted of 0.3 ml of 0.133 M pyrophosphate buffer (pH 8.3) containing
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