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- D53927
- 2025年10月17日
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1mg/5mg
| 规格： | 1mg | 产品价格： | ￥215.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥534.0 |
| 产品编号 | D53927 |
| 英文名称 | EAAT2 activator 1 |
| 英文别名 | F2005-0304; 3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine |
| 理论分子量 | 331.8 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | F2005-0304 is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes. |
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文献和实验. Moore, F.E., Reyon, D., Sander, J.D., Martinez, S.A., Blackburn, J.S., Khayter, C., Ramirez, C.L., Joung, J.K., and Langenau, D.M. 2012. Improved somatic mutagenesis in zebrafish using transcription activator
Determination of Phospholipase C-or Phospholipase D-Catalyzed Phosphatidylcholine Hydrolysis
Signal-activated phospholipase-catalyzed hydrolysis of phosphatidylcholin involves three distinct enzymes: phospholipase A2 , phospholipase C (PLC), and phospholipase D (PLD) (1 ). PLC-catalyzed hydrolysis generates sn -1,2-diacylglycerol
the authors to conclude that AP-1 is likely to be an essential activator of BIC gene transcription, at least during the inflammatory response. Consistent with this conclusion, Baltimore and colleagues noted that several AP-1 binding sites are present
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