- ￥980 - 2680
- Bioss
- bs-101915P
- 2026年10月10日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
相关阅读
AI 赋能培养基定制开发：CHO 培养基是如何实现产量提升Cytoscape 教程来了！快速实现顶刊同款通路网络图五大应用案例：Mustang Q 膜层析应用全解析1 个小工具，一次性搞定流程图、质粒图谱和信号通路图- 详细信息
- 技术资料
- 规格：
20ug/50ug/100ug
| 规格： | 20ug | 产品价格： | ￥980.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥1880.0 |
| 规格： | 100ug | 产品价格： | ￥2680.0 |
| 产品编号 | bs-101915P |
| 英文名称 | Recombinant Human PTK7 Protein, N-His |
| 英文别名 | Protein-tyrosine kinase 7; Inactive tyrosine-protein kinase 7; CCK4; PTK7; Colon carcinoma kinase 4; Tyrosine-protein kinase-like 7; CCK-4; Pseudo tyrosine kinase receptor 7 |
| 性状 | Lyophilized |
| 纯化方法 | AC |
| 理论分子量 | 26.87 kDa |
| 储存液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 研究领域 | Metabolism > Types of disease > Obesity Signal Transduction > Protein Phosphorylation > Tyrosine Kinases Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚细胞定位 | Membrane. Cell junction. Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells. |
| 组织特异性 | Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon. |
| 翻译后修饰 | MMP14 cleaves PTK7 between Pro-621 and Leu-622 generating an N-terminal soluble (70 kDa) fragment and a membrane C-terminal (50 kDa) fragment. Proteolysis by MMP14 regulates PTK7 function in non-canonical Wnt signaling pathway. |
| 相似性 | Belongs to the protein kinase superfamily. Cell membrane Tyr protein kinase family. Insulin receptor subfamily.Cell membrane _x000D_ Contains 7 Ig-like C2-type (immunoglobulin-like) domains.Cell membrane _x000D_ Contains 1 protein kinase domain |
| 功能 | Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
rHu PTK7 | CCK4 Protein, N-His(bs-101915P)-20ug/50ug/100ug
￥980 - 2680
