- ￥880
- Bioss
- bs-15079P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15079P |
| 英文名称 | FAAP20 Antibody Blocking Peptide |
| 中文名称 | 1号染色体开放阅读框86封闭多肽 |
| 英文别名 | C1orf86; CA086_HUMAN; Chromosome 1 open reading frame 86; FP7162; RP11-181G12.3; Uncharacterized protein C1orf86. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚基 | Component of the Fanconi anemia (FA) complex. Interacts with FANCA; interaction is direct. Interacts with REV1. Reported to bind monoubiquitinated REV1; however it binds better to non-ubiquitinated REV1 (PubMed:22266823). |
| 亚细胞定位 | Nucleus. Chromosome. Note=Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8. |
| 相似性 | Contains 1 UBZ-type zinc finger. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1. |
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FAAP20 Antibody Blocking Peptide(bs-15079P)-500ug
￥880
