- ￥2980
- Bioss
- bs-0495R-Cy3
- 2025年10月15日
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100ul
| 产品编号 | bs-0495R-Cy3 |
| 英文名称 | Selenoprotein W Rabbit pAb, Cy3 conjugated |
| 中文名称 | Cy3标记的硒蛋白W抗体 |
| 英文别名 | MGC105482; SelW; SEPW1; Selenoprotein W; SELW_RAT; SELW_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse Selenoprotein W |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with DPYSL2, PRDX1, YWHAB, YWHAG, HSP70 and HSP90. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Ubiquitously expressed with highest levels in skeletal muscle and heart, moderate levels in brain, spinal cord, thyroid, spleen, prostate, ovary, small intestine and colon, and lowest levels in liver and lymph node. |
| 相似性 | Belongs to the SelWTH family. SELW subfamily. |
| 功能 | Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is highly expressed in skeletal muscle and brain. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Studies in mouse show that this selenoprotein is involved in muscle growth and differentiation, and in the protection of neurons from oxidative stress during neuronal development. A pseudogene for this locus has been identified on chromosome 10. [provided by RefSeq, May 2017]. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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文献和实验相关实验
Construction and Use of Glycan Microarrays
) Printing buffer (see recipe ) Controls: unmodified BSA and HSA (negative controls) and BSA conjugated with Cy3 or Alexa Fluor 647
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Selenoprotein W Rabbit pAb, Cy3 conjugated(bs-0495R-Cy3)-100ul
￥2980
