GPM6A Rabbit pAb, FITC conjugated(bs-10757R-FITC)-100ul产品图

GPM6A Rabbit pAb, FITC conjuga

ted(bs-10757R-FITC)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-10757R-FITC
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-10757R-FITC
    英文名称GPM6A Rabbit pAb, FITC conjugated
    中文名称FITC标记的神经细胞膜糖蛋白M6a抗体
    英文别名GPM6A; GPM6A_HUMAN; M6a; M6 a; M6-a; Neuronal membrane glycoprotein M6-a.
    产品应用Flow-Cyt=1μg/Test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human GPM6A
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Interacts with OPRM1
    亚细胞定位Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine. Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons.
    相似性Belongs to the myelin proteolipid protein family.
    功能Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料GPM6A (Glycoprotein M6A) is a Protein Coding gene. GO annotations related to this gene include calcium channel activity. An important paralog of this gene is GPM6B.

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}
    {IF}{1:100-500}

     

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    图标文献和实验
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    • Fluorochrome Absorption and Emission

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