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100ul
| 产品编号 | bs-13444R-AP |
| 英文名称 | GLYATL1 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的甘胺酸-N-酰基转移酶样1抗体 |
| 英文别名 | Acyl CoA glycine N acyltransferase like protein 1; EC 2.3.1.13; FLJ26507; FLJ34646; GATF C; GATFC; Glycine N acyltransferase like 1; GNAT; MGC15397; MGC15937; GLYL1_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GLYATL1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Signal Transduction > Metabolism > Amino Acids Signal Transduction > Metabolism > Mitochondrial |
| 亚细胞定位 | Mitochondrial |
| 组织特异性 | Expressed in liver and kidney and, at lower levels, in pancreas, testis, ovary and stomach. |
| 相似性 | Belongs to the glycine N-acyltransferase family. |
| 功能 | GLYATL1 is a mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. It can conjugate a multitude of substrates to form a variety of N-acylglycines. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GLYATL1 is a 302 amino acid mitochondrial acyltransferase that transfers the acyl group to the N-terminus of glycine. GLYATL1 can also conjugate a multitude of substrates to form a variety of N-acylglycines. A member of the glycine N-acyltransferase family, GLYATL1 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q12.1. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验SDS-PA gels, and subsequent detection of proteins using rabbit antisera and alkaline phosphatase-conjugated goat-anti-rabbit IgG, detected using bromo-chloro-indolyl phosphate (BCIP) and Nitro-blue tetrazolium (NBT) salts. ・
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Literature Cited Armstrong, J.F., Kaufman, M.H., Harrison, D.J., and Clarke, A.R. 1995. High‐frequency developmental abnormalities in p53‐deficient mice. Curr
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