- ￥4344 - 14040
- Elabscience
- 湖北武汉
- AN00807E
- 2025年09月28日
- WB;IHC-p;IF;IP
- Mouse
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 形态：
液体
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 适应物种：
Human;Mouse;Rat
- 保质期：
12个月
- 库存：
999
- 宿主：
Mouse
- 应用范围：
WB;IHC-p;IF;IP
- 抗体英文名：
APC Anti-Mouse CD206 Antibody[Y17-505]
- 规格：
100Tests/50Tests/100Tests×2
| 规格： | 100Tests | 产品价格： | ￥7800.0 |
|---|---|---|---|
| 规格： | 50Tests | 产品价格： | ￥4344.0 |
| 规格： | 100Tests×2 | 产品价格： | ￥14040.0 |
APC Anti-Mouse CD206 Antibody[Y17-505]
| Alternate Names |
MMR, macrophage mannose receptor, MR, mannose receptor, MRC1, CD206抗体, CD206流式抗体, 小鼠CD206, 小鼠CD206抗体, 小鼠CD206流式抗体, AN00807
|
| Cellular Localization |
Membrane;Endosome
|
| Clone No | |
| Isotype |
Rat IgG2a, κ
|
| Leadtime |
咨询
|
| Background |
The Y17-505 monoclonal antibody specifically binds to CD206 which is also known as the Macrophage mannose receptor (MMR, MR) or Mannose receptor, C type 1 (Mrc1). CD206 is a type I transmembrane glycoprotein of approximately 175 kDa that belongs to the C-type lectin superfamily. It is expressed at the cell surface and intracellularly by macrophages, Langerhans cells, dendritic cells, and endothelial cells within hepatic and lymphoid tissues. This pattern recognition receptor binds to endogenous and microbial glycoconjugates containing mannose, fucose, or N-acetylglucosamine through its C-type lectin-like carbohydrate recognition domains (CRD). CD206 also contains a cysteine-rich domain that enables binding to sulfated carbohydrate antigens. This receptor enables macrophages and other specialized cells to maintain tissue homeostasis as well as to internalize microbes or their components by phagocytosis or endocytosis. CD206 thus plays important roles in mediating innate immunity, eg, enabling phagocytosis, as well as in processing and presenting antigens for the generation and expression of adaptive immunity. Moreover, CD206 has been associated with leucocyte homing and cancer cell metastasis.
|
| Abbre |
CD206
|
| Swissprot |
Q61830
|
| Host |
Rat
|
| Reactivity |
Mouse
|
| Clonality |
Monoclonal
|
| Isotype Control | |
| Applications | |
| Form |
Liquid
|
| Concentration |
5 μL/Test
|
| Conjugation |
APC
|
| Conjugation Information |
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
|
| Spectrum |
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration Date |
12个月
|
| Shipping |
冰袋
|
| Gene ID |
17533
|
APC Anti-Mouse CD206 Antibody[Y17-505]Elabscience®流式抗体致力于为您的流式细胞分析实验带来更优质的体验，已有3,000+指标，选用经典克隆株纯化抗体，产品涵盖抗人/大鼠/小鼠等，指标丰富。
APC Anti-Mouse CD206 Antibody[Y17-505]Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
APC Anti-Mouse CD206 Antibody[Y17-505]产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验Stimulation of Anti-HIV-1 Cytotoxic T Lymphocytes by Dendritic Cells
Dendritic cells (DC) are highly specialized antigen-presenting cells (APC) in both primary and secondary T-cell responses. This may be related to their expression of high levels of MHC class I and II antigens (1 -4 ), costimulatory
MHC I STREPTAMERS® 检测与分离抗原特异性 (CD8+ T) 细胞
体，实现了对抗原特异性 (CD8+ T) 细胞的检测和分离 (如，流式分析) 。此技术的特点在于，荧光或磁性微珠等标记物可以通过使用 Biotin (生物素) 而去除，保留了细胞的真实特性，得到的功能性的，label-free 的细胞可用于下游的实验研究。 1) MHC I STREPTAMERS® 技术解析 MHC I STREPTAMERS® 由两部分组成： · MHC I-Strep，即连接了 Twin-Strep-tag® 和抗原肽的 MHC I 分子。 · 荧光 (PE/APC)
and H2-A and E in mice) for CD4+ T cells. However, a significant proportion of T cells recognize peptide antigens bound to nonclassical MHC class Ib molecules such as the human HLA-E (mouse analog Qa1) (4 ) and mouse H2-M3 (5 ). In addition, some T
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