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- 文献和实验
- 技术资料
- 保存条件:
本品可在2-8°C保存12个月。请避免长期接触阳光,不要冻结。
- 保质期:
12个月
- 规格:
20Tests/100Tests/100Tests×2
| 规格: | 20Tests | 产品价格: | ¥900.0 |
|---|---|---|---|
| 规格: | 100Tests | 产品价格: | ¥2640.0 |
| 规格: | 100Tests×2 | 产品价格: | ¥3960.0 |
| Alternate Names |
Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b
|
| Cellular Localization |
Membrane
|
| Clone No |
HI11b
|
| Isotype |
Mouse IgG2b, κ
|
| Leadtime |
咨询
|
| Background |
CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
|
| Abbre |
CD11b
|
| Swissprot |
P11215
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Clonality |
Monoclonal
|
| Isotype Control |
Elab Fluor®700 Mouse IgG2b, κ Isotype Control[MPC-11]
|
| Applications |
FCM
|
| Form |
Liquid
|
| Conjugation |
Elab Fluor®700
|
| Conjugation Information |
Elab Fluor® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration Date |
12个月
|
| Shipping |
冰袋
|
| Gene ID |
3684
|
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
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换液会导致细胞漂浮。 Elabscience®相关产品推荐 货号 产品名称 E-CK-A103 人外周血单个核细胞分离液(P 1.077) E-AB-F1137C FITC 标记抗人 CD45 抗体 [HI30] E-AB-F1081D PE 标记抗小鼠/人/猴 CD11b 抗体 [M1/70] AN00213Q Elab Fluor® Violet 450 标记抗人 CD14 抗体 [H332-1B10] E-AB-F1299M Elab Fluor® 647
Elabscience 巨噬细胞三大功能及检测方案全梳理,看完少走90%弯路!
悬液的表型鉴定和功能分析。巨噬细胞没有类似于T细胞(CD4/CD8)那样明确的单一区分抗原,因此需要使用一组标志物的组合来鉴定巨噬细胞。对于小鼠巨噬细胞,常用的组合包括F4/80、CD11b、Ly6C和THY-1等。通过多色荧光标记和流式细胞仪分析,可以在异质性细胞群中精确地鉴定和分选出巨噬细胞。 图5. C57BL/6J腹腔炎症小鼠取腹水样本,使用PE Anti-Mouse/Human/Monkey CD11b Antibody[M1/70](E-AB-F1081D)、Elab Fluor®
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Violet 421 标记抗小鼠MHC II(I-A/I-E)抗体[M5/114] AN00821Q2 Elab Bright™ Violet 421 标记大鼠IgG2b,κ同型对照抗体[R35-38] E-AB-F1136S Elab Fluor® Red 780 标记抗小鼠CD45抗体[30-F11] E-AB-F1081T Elab Fluor® Violet 610 标记抗小鼠/人/猴CD11b抗体[M1/70] E-AB-F1186C FITC 标记抗小鼠CD64/FcγRI
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