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- bs-6051P
- 2025年10月15日
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500ug
| 产品编号 | bs-6051P |
| 英文名称 | HPGD Antibody Blocking Peptide |
| 中文名称 | 前列腺素脱氢酶1封闭多肽 |
| 英文别名 | PGDH_HUMAN; 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; EC:1.1.1.141; 15-PGDH; 15 PGDH; 15PGDH; Eicosanoid/docosanoid dehydrogenase [NAD(+)] (EC:1.1.1.-; EC:1.1.1.232; Prostaglandin dehydrogenase 1; Short chain dehydrogenase/reductase family 36C member 1; PGDH1; SDR36C1; PGDH; PGDH1; PHOAR1; |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Macrophage / Inflamm. Signal Transduction > Signaling Pathway > Lipid Signaling > Prostaglandins |
| 亚基 | Homodimer. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Detected in colon epithelium (at protein level). |
| 相似性 | Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
| 功能 | Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]. |
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文献和实验deposit: NoPrice_code: AAvailability in cell line catalogues: ATCC CCL 61; IZSBS BS CL15; DSMZ ACC 110;Bibliographic references:J Exp Med 1958;108:945 Proc Nat Acad Sci USA 1968;60:1275CHO-K1 (hamster, Chinese, ovary)Morphology: epithelial-likeSpecies
后置-20℃保存 20×SSC 10×PBS （DEPC处理的）含50%甲酰胺的杂交液（HS）--- 1ml分装后置-20℃保存 10×阻断液（10×BS） Buffer I Buffer II Buffer III 探针（P） 抗Dig-Ap NBT/BCIP 二、操作流程: 1） 脱蜡至水： 二甲苯5min×2 → 90%乙醇5min → DEPC水洗涤5min×2 2） 杂交前处理： 1×PBS洗涤5min → 蛋白酶K（终浓度20ug/ml in PBS）37℃
in Renal Cancer (p 73-96) Rosamonde E. Banks, Peter J. Selby Chapter 6: Heat Shock Protein 27 in Cancer (p 97-109) Dr. Cecilia Sarto, Dr. Fulvio Magni, BS. Cristina Valsecchi, Prof. Dr. Paolo Mocarelli Chapter 7: Proteomic Approaches for Biomarker
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