EXOSC6 重组单克隆抗体, PBS Only  84346-4-PBS

EXOSC6 重组单克隆抗体, PBS Only 8434

6-4-PBS
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  • ¥5800
  • Proteintech已认证
  • 84346-4-PBS
  • 2025年10月09日
  • WB, IF/ICC, FC (Intra), Indirect ELISA
  • Rabbit
  • human
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant human EXOSC6 protein

    • 亚型

      IgG

    • 保存条件

      Store at -80°C.

    • 克隆性

      Recombinant

    • 标记物

      Unconjugated

    • 适应物种

      human

    • 宿主

      Rabbit

    • 应用范围

      WB, IF/ICC, FC (Intra), Indirect ELISA

    • 靶点

      EXOSC6

    • 抗体英文名

      EXOSC6 Recombinant monoclonal antibody, PBS Only

    • 抗体名

      EXOSC6 Recombinant monoclonal antibody, PBS Only

    • 规格

      100ug

    产品信息

    84346-4-PBS targets EXOSC6 in WB, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.

    经测试应用 WB, IF/ICC, FC (Intra), Indirect ELISA
    经测试反应性 human
    免疫原

    CatNo: Ag33513

    Product name: Recombinant human EXOSC6 protein

    Source: e coli.-derived, PGEX-4T

    Tag: GST

    Domain: 1-272 aa of NM_058219

    Sequence: MPGDHRRIRGPEESQPPQLYAADEEEAPGTRDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGGGPAGAGGEAPAALRGRLLCDFRRAPFAGRRRRAPPGGCEERELALALQEALEPAVRLGRYPRAQLEVSALLLEDGGSALAAALTAAALALADAGVEMYDLVVGCGLSLAPGPAPTWLLDPTRLEEERAAAGLTVALMPVLNQVAGLLGSGEGGLTESWAEAVRLGLEGCQRLYPVLQQSLVRAARRRGAAAQP

    宿主/亚型 Rabbit / IgG
    抗体类别 Recombinant
    产品类型 Antibody
    全称 exosome component 6
    别名 241535C3, EAP4, exosome component 6, hMtr3, hMtr3p
    计算分子量28kd
    观测分子量28-32 kDa
    GenBank蛋白编号NM_058219
    基因名称 EXOSC6
    Gene ID (NCBI) 118460
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein A purfication
    UNIPROT IDQ5RKV6
    储存缓冲液 PBS only, pH 7.3.
    储存条件Store at -80°C.
    The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

    背景介绍

    EXOSC6 (exosome component 6), also known as p11 or MTR3. The calculated molecular weight of EXOSC6 is 28 kDa. And it has low tissue specificity. The gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. It is also a component of the RNA exosome complex (PMID: 29906447). The composition of human exosome is similar to its yeast counterpart. EXOSC6 is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.

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