- ￥5800
- Proteintech
- 68191-1-PBS
- 2025年10月09日
- WB, ELISA
- Mouse
- human, mouse, rat, pig, rabbit
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human GNAQ protein
- 亚型：
IgG2b
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse, rat, pig, rabbit
- 宿主：
Mouse
- 应用范围：
WB, ELISA
- 靶点：
GNAQ
- 抗体英文名：
GNAQ Monoclonal antibody, PBS Only
- 抗体名：
GNAQ Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
68191-1-PBS targets GNAQ in WB, ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
| 经测试应用 | WB, ELISA |
| 经测试反应性 | human, mouse, rat, pig, rabbit |
| 免疫原 |
CatNo: Ag26178 Product name: Recombinant human GNAQ protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 84-205 aa of BC057777 Sequence: FTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVD |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | guanine nucleotide binding protein (G protein), q polypeptide |
| 别名 | 2H5G6, CMC1, G ALPHA q, GAQ, Guanine nucleotide-binding protein alpha-q |
| 计算分子量 | 42 kDa |
| 观测分子量 | 38-40 kDa |
| GenBank蛋白编号 | BC057777 |
| 基因名称 | GNAQ |
| Gene ID (NCBI) | 2776 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P50148 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GNAQ is a proto-oncogene closely related to the α subunit of guanine nucleotide-binding proteins (G proteins) that serve as key intermediates between membrane-bound G-protein-coupled receptors (GPCRs) and GPCR signalling nodes. Aberrant expression and activity of G proteins and GPCRs are frequently associated with tumorigenesis. Recent studies show that oncogenic activating mutations in GNAQ are present in 80% of the melanomas. The calculated molecular weight of GNAQ is 42 kDa. This antibody can detect a band of 38-40 kDa in SDS-PAGE. (PMID: 33993733)
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