- ￥5800
- Proteintech
- 66962-1-PBS
- 2025年10月09日
- WB, IHC, ELISA
- Mouse
- human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human PAPPA protein
- 亚型：
IgG1
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Mouse
- 应用范围：
WB, IHC, ELISA
- 靶点：
PAPPA
- 抗体英文名：
PAPPA Monoclonal antibody, PBS Only
- 抗体名：
PAPPA Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
66962-1-PBS targets PAPPA in WB, IHC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IHC, ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag11863 Product name: Recombinant human PAPPA protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1279-1627 aa of BC078657 Sequence: ACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEPFMGDNYCDAINNRAFCNYDGGDCCTSTVKTKKVTPFPMSCDLQGDCACRDPQAQEHSRKDLQGYSHG |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | pregnancy-associated plasma protein A, pappalysin 1 |
| 别名 | 1G5A7, ASBABP2, DIPLA1, EC:3.4.24.79, IGFBP 4ase |
| 计算分子量 | 1627 aa, 181 kDa |
| 观测分子量 | 180-220 kDa |
| GenBank蛋白编号 | BC078657 |
| 基因名称 | PAPPA |
| Gene ID (NCBI) | 5069 |
| RRID | AB_2882285 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q13219 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Pregnancy-associated plasma protein A (PAPPA) is a metalloproteinase secreted by human placenta, and it can interact with IGF-binding proteins (IGFBPs) to regulate the proteolysis and the bioavailability of insulin-like growth factor (IGF). Circulating PAPPA represents a consolidated biomarker in combined first-trimester screening tests, allowing an early prenatal diagnosis of chromosomal abnormalities, preeclampsia, and intrauterine growth restriction risk. PAPPA is highly expressed in placenta and pregnancy serum (PMID: 34974815, 34974815).
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