- ￥5800
- Proteintech
- 82993-6-PBS
- 2025年10月09日
- WB, IHC, Indirect ELISA
- Rabbit
- human
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- 详细信息
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
WB, IHC, Indirect ELISA
- 靶点：
Endoglin/CD105
- 抗体英文名：
Endoglin/CD105 Recombinant monoclonal antibody, PBS Only
- 抗体名：
Endoglin/CD105 Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
82993-6-PBS targets Endoglin/CD105 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IHC, Indirect ELISA |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | endoglin |
| 别名 | CD105, 241196G9, HHT1, ENG, Endoglin |
| 计算分子量 | 71 kDa |
| 观测分子量 | 75-90 kDa |
| GenBank蛋白编号 | BC014271 |
| 基因名称 | CD105 |
| Gene ID (NCBI) | 2022 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P17813 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)
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