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- 详细信息
- 技术资料
- 免疫原:
Recombinant human BRD7 protein
- 亚型:
IgG
- 保存条件:
Store at -80°C.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
human, mouse
- 宿主:
Rabbit
- 应用范围:
WB, Indirect ELISA
- 靶点:
BRD7
- 抗体英文名:
BRD7 Recombinant monoclonal antibody, PBS Only
- 抗体名:
BRD7 Recombinant monoclonal antibody, PBS Only
- 规格:
100ug
产品信息
86176-2-PBS targets BRD7 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag1461 Product name: Recombinant human BRD7 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-353 aa of BC050728 Sequence: MGKKHKKHKSDKHLYEEYVEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDHDKHKDRKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSLKQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSKENKKKDKDMLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLGL |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | bromodomain containing 7 |
| 别名 | BP75, Bromodomain-containing protein 7, CELTIX1, NAG4, Protein CELTIX 1 |
| 计算分子量 | 651 aa, 74 kDa |
| 观测分子量 | 74-78 kDa |
| GenBank蛋白编号 | BC050728 |
| 基因名称 | BRD7 |
| Gene ID (NCBI) | 29117 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9NPI1 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
BRD7 (bromodomain containing 7), is a subunit of poly-bromo-associated BRG1-associated factor (PBAF)-specific Swi/Snf chromatin remodeling complexes.BRD7 is proposed as a tumor suppressor protein, since its identification as an important component of both functional p53 and BRCA1 (breast cancer 1, early onset) pathways. BRD7 could down-regulate the GSK3beta phosphotransferase activity as dephosphorylation of GSK3B at 'Tyr-216', thus activate the Wnt signaling pathway in a DVL1-dependent manner.
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