- ￥5800
- Proteintech
- 67051-1-PBS
- 2025年10月09日
- WB, ELISA
- Mouse
- human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human IL-4R protein
- 亚型：
IgG1
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Mouse
- 应用范围：
WB, ELISA
- 靶点：
IL-4RA/CD124
- 抗体英文名：
IL-4RA/CD124 Monoclonal antibody, PBS Only
- 抗体名：
IL-4RA/CD124 Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
67051-1-PBS targets IL-4RA/CD124 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag28411 Product name: Recombinant human IL-4R protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 26-232 aa of NM_000418 Sequence: MKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQH |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | interleukin 4 receptor |
| 别名 | IL4R, 1E4C11, CD124, IL 4 binding protein, IL 4 receptor subunit alpha |
| 计算分子量 | 90 kDa |
| 观测分子量 | 120 kDa |
| GenBank蛋白编号 | NM_000418 |
| 基因名称 | IL-4R |
| Gene ID (NCBI) | 3566 |
| RRID | AB_2882364 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P24394 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
IL-4 receptor alpha chain (IL-4RA), also known as CD124, is a transmembrane glycoprotein expressed on a wide variety of hematopoietic and non-hematopoietic cells. It is a receptor for both IL-4 and IL-13. IL-4RA can complex with the common gamma chain (IL-2R gamma or CD132) and utilizes JAK1 and JAK2 for signal transduction, while complexes of IL-4RA with IL-13RA1 subunit mediate signals via JAK2 and Tyk2. The IL-4 response is involved in promoting Th2 differentiation. The IL-4/IL-13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.
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