- ￥5800
- Proteintech
- 66978-1-PBS
- 2025年10月09日
- WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
- Mouse
- rat, mouse, human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human CUL1 protein
- 亚型：
IgG2b
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
rat, mouse, human
- 宿主：
Mouse
- 应用范围：
WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
- 靶点：
CUL1
- 抗体英文名：
CUL1 Monoclonal antibody, PBS Only
- 抗体名：
CUL1 Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
66978-1-PBS targets CUL1 in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with rat, mouse, human samples.
| 经测试应用 | WB, IHC, IF/ICC, FC (Intra), Indirect ELISA |
| 经测试反应性 | rat, mouse, human |
| 免疫原 |
CatNo: Ag28399 Product name: Recombinant human CUL1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 111-462 aa of BC034318 Sequence: YCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVLSSGSWPFQQFCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | cullin 1 |
| 别名 | Cullin-1, Cullin1, CUL-1, 1B6D10 |
| 计算分子量 | 90 kDa |
| 观测分子量 | 85 kDa |
| GenBank蛋白编号 | BC034318 |
| 基因名称 | CUL1 |
| Gene ID (NCBI) | 8454 |
| RRID | AB_2882298 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q13616 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases. Humans express seven cullin proeins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.
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