- ￥5800
- Proteintech
- 85923-1-PBS
- 2025年10月09日
- WB, IHC, Indirect ELISA
- Rabbit
- human, mouse, pig
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- 详细信息
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human, mouse, pig
- 宿主：
Rabbit
- 应用范围：
WB, IHC, Indirect ELISA
- 靶点：
Neuroserpin
- 抗体英文名：
Neuroserpin Recombinant monoclonal antibody, PBS Only
- 抗体名：
Neuroserpin Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
85923-1-PBS targets Neuroserpin in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.
| 经测试应用 | WB, IHC, Indirect ELISA |
| 经测试反应性 | human, mouse, pig |
| 免疫原 |
CatNo: Eg2819 Product name: Recombinant Human Neuroserpin protein (rFc Tag) Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 17-410 aa of NM_005025.4 Sequence: TGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| 别名 | Serpin I1, Peptidase inhibitor 12, PI 12, PI12, PI-12 |
| 计算分子量 | 46 kDa |
| 观测分子量 | 46 kDa |
| GenBank蛋白编号 | NM_005025.4 |
| 基因名称 | Neuroserpin |
| Gene ID (NCBI) | 5274 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q99574 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Neuroserpin is a member of the serpin family of serine protease inhibitors predominantly expressed in the nervous system, such as s the cerebral cortex, hippocampus and the spinal cord.Neuroserpin exerts protective effects in neurons against excitotoxicity both in vitro and in vivo. Its proteolytic inhibitory activity is shown to protect neurons against damage caused by plasmin activation. Mice overexpressing neuroserpin exhibited loss of tPA activity in the brain. Overexpression of neuroserpin in primary neurons leads to increased dendritic arborization and altered dendritic spine shape.
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