- ￥5800
- Proteintech
- 83859-1-PBS
- 2026年05月29日
- WB, IF/ICC, FC (Intra), ELISA
- Rabbit
- human
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- 详细信息
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
WB, IF/ICC, FC (Intra), ELISA
- 靶点：
HEC1/HEC/NDC80
- 抗体英文名：
HEC1/HEC/NDC80 Recombinant monoclonal antibody, PBS Only
- 抗体名：
HEC1/HEC/NDC80 Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
83859-1-PBS targets HEC1/HEC/NDC80 in WB, IF/ICC, FC (Intra), ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IF/ICC, FC (Intra), ELISA |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | NDC80 homolog, kinetochore complex component (S. cerevisiae) |
| 别名 | NDC80, Kinetochore protein Hec1, hsNDC80, HsHec1, HEC1 |
| 观测分子量 | 74 kDa |
| GenBank蛋白编号 | / |
| 基因名称 | NDC80 |
| Gene ID (NCBI) | 10403 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | O14777 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NDC80 complex is a heterotetrameric protein complex comprised of Hec1 (also called Ndc80), Nuf2, Spc24, and Spc25. Mis12 complex (bound to CENP-C or CENP-T) or CDK1-phosphorylated CENP-T to anchor the NDC80 complex to the kinetochore. HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.
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