- ￥5800
- Proteintech
- 68121-1-PBS
- 2025年10月09日
- WB, IF/ICC, Indirect ELISA
- Mouse
- Human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human MAN1B1 protein
- 亚型：
IgG2b
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 宿主：
Mouse
- 应用范围：
WB, IF/ICC, Indirect ELISA
- 靶点：
MAN1B1
- 抗体英文名：
MAN1B1 Monoclonal antibody, PBS Only
- 抗体名：
MAN1B1 Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
68121-1-PBS targets MAN1B1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.
| 经测试应用 | WB, IF/ICC, Indirect ELISA |
| 经测试反应性 | Human |
| 免疫原 |
CatNo: Ag28302 Product name: Recombinant human MAN1B1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 350-699 aa of BC002953 Sequence: LFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFLPGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFFLGETLKYLFLLFSDDPNLLSLDAYVFNTEAHPLPIWTPA |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | mannosidase, alpha, class 1B, member 1 |
| 别名 | ER alpha 1,2 mannosidase, ER mannosidase 1, ERMan1, MAN1B1, MANA ER |
| 计算分子量 | 80 kDa |
| 观测分子量 | 80 kDa |
| GenBank蛋白编号 | BC002953 |
| 基因名称 | MAN1B1 |
| Gene ID (NCBI) | 11253 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9UKM7 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MAN1B1, also known as ERMAN1, MANA-ER, belongs to the glycosyl hydrolase 47 family. MAN1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation, specifically converting Man9GlcNAc to Man8GlcNAc isomer B. At high enzyme concentrations, it further trims the carbohydrates to Man5-6GlcNAc2 (PMID: 18003979). Mutations in MAN1B1 cause autosomal-recessive intellectual disability. This gene has been associated with Rafiq syndrome (PMID: 21763484).
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