- ￥5800
- Proteintech
- 86565-1-PBS
- 2025年10月09日
- WB, Indirect ELISA
- Rabbit
- mouse
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- 详细信息
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
mouse
- 宿主：
Rabbit
- 应用范围：
WB, Indirect ELISA
- 靶点：
CCL12/MCP-5
- 抗体英文名：
Mouse CCL12/MCP-5 Recombinant monoclonal antibody, PBS Only
- 抗体名：
Mouse CCL12/MCP-5 Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
86565-1-PBS targets CCL12/MCP-5 in WB, Indirect ELISA applications and shows reactivity with mouse samples.
| 经测试应用 | WB, Indirect ELISA |
| 经测试反应性 | mouse |
| 免疫原 |
CatNo: Eg3315 Product name: Recombinant Mouse CCL12/MCP-5 protein (rFc Tag) (HPLC verified) Source: mammalian cells-derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 23-104 aa of NM_011331.2 Sequence: GPDAVSTPVTCCYNVVKQKIHVRKLKSYRRITSSQCPREAVIFRTILDKEICADPKEKWVKNSINHLDKTSQTFILEPSCLG |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | chemokine (C-C motif) ligand 12 |
| 别名 | C-C motif chemokine 12, Ccl12, MCP-1-related chemokine, Mcp5, MCP-5 |
| 计算分子量 | 12KD |
| GenBank蛋白编号 | NM_011331.2 |
| 基因名称 | Ccl12 |
| Gene ID (NCBI) | 20293 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q62401 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CCL12 (monocyte chemotactic protein-5, MCP-5) is a murine CC-chemokine encoded within the chemokine cluster on chromosome 11. It is the closest murine homologue of human MCP-1 (CCL2), sharing 66 % amino-acid identity, and signals exclusively through the G-protein-coupled receptor CCR2. CCL12 is produced by stromal cells, astrocytes, macrophages and, under inflammatory conditions, by lung and bone-marrow stromal cells. Its receptor, CCR2, is expressed on monocytes, memory T cells, NK cells, dendritic cells and basophils. Consequently, CCL12 potently chemoattracts monocytes, lymphocytes, eosinophils and bone-marrow-derived fibrocytes, but not neutrophils.
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