- ￥600 - 3000
- Proteintech
- 65620-1-MR
- 2026年05月29日
- FC
- Mouse
- human, non-human primates
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- 文献和实验
- 技术资料
- 亚型：
IgG2a
- 保存条件：
Store at 2-8°C. Stable for one year after shipment.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human, non-human primates
- 宿主：
Mouse
- 应用范围：
FC
- 靶点：
CD25/IL-2RA
- 抗体英文名：
Anti-Human CD25/IL-2RA (BC96) Mouse IgG2a Recombinant Antibody
- 抗体名：
Anti-Human CD25/IL-2RA (BC96) Mouse IgG2a Recombinant Antibody
- 规格：
100ug/500ug/1mg
| 规格： | 100ug | 产品价格： | ￥600.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥2200.0 |
| 规格： | 1mg | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive FC detected in | PHA treated human PBMCs |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65620-1-MR targets CD25/IL-2RA in FC applications and shows reactivity with human, non-human primates samples.
| 经测试应用 | FC |
| 经测试反应性 | human, non-human primates |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | interleukin 2 receptor, alpha |
| 别名 | CD25, BC96, IL 2 RA, IL 2 receptor subunit alpha, IL 2R subunit alpha |
| 计算分子量 | 272 aa, 31 kDa |
| GenBank蛋白编号 | BC156627 |
| 基因名称 | IL2RA |
| Gene ID (NCBI) | 3559 |
| RRID | AB_3670363 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P01589 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor following T lymphocyte activation. The receptor for IL-2 has three forms, generated by different combinations of three different proteins, the alpha chain (IL-2R alpha), the beta chain (IL-2R beta), and the gamma chain (IL-2R gamma) (PMID: 8476561). IL-2R alpha (also known as CD25) is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. CD25 is also found on natural CD4+Foxp3+ Treg cells and a subset of human CD4+ memory T cells (PMID: 22585674).
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文献和实验ANTIBODY BINDING TO PROTEIN A AND PROTEIN G
A Protein G Human IgG1 ++++ ++++ Human IgG2 ++++ ++++ Human IgG3 - ++++ Human IgG4 ++++ ++++ Mouse IgG1 + ++++ Mouse IgG2a
血管里的“斑块清洁工”来了！CD25+调节性T细胞变身CAR-Treg，效果惊人
于对机体免疫调节机制的了解，最终为相关疾病的治疗开辟新的免疫治疗途径。 为鼎力协助科研和药企人员针对IL-2RA（CD25）在多种免疫疾病和肿瘤中的临床应用研究，CUSABIO推出IL-2RA（CD25）活性蛋白（Code: CSB-MP011649HU3），助力您在IL-2RA（CD25）机制方面的研究或其潜在临床价值的探索。 ● IL-2RA（CD25）蛋白 Recombinant Human Interleukin-2 receptor subunit alpha(IL2RA),partial
(9 ). Because its systemic administration was shown to mediate the regression of some mouse tumors (10 ), TNF-α has attracted much attention as a potential antitumor reagent (11 ). However, the problem of its dose-dependent toxicity has been particularly apparent in human
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