- ￥5800
- Proteintech
- 66081-1-PBS
- 2025年10月09日
- WB, IHC, IF/ICC, ELISA
- Mouse
- human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human IFITM3 protein
- 亚型：
IgG1
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Mouse
- 应用范围：
WB, IHC, IF/ICC, ELISA
- 靶点：
IFITM2/3
- 抗体英文名：
IFITM2/3 Monoclonal antibody, PBS Only
- 抗体名：
IFITM2/3 Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
66081-1-PBS targets IFITM2/3 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IHC, IF/ICC, ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag17863 Product name: Recombinant human IFITM3 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-133 aa of BC006794 Sequence: MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVLIFQAYG |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | interferon induced transmembrane protein 3 (1-8U) |
| 别名 | IFITM3, 1 8U, 2E8D12, DSPA2b, Interferon-induced transmembrane protein 3 |
| 观测分子量 | 15-20 kDa |
| GenBank蛋白编号 | BC070243 |
| 基因名称 | IFITM3 |
| Gene ID (NCBI) | 10410 |
| RRID | AB_11182821 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q01628 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
IFITM3, also named as interferon-inducible protein 1-8U, belongs to the CD225 family. It is IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus, by inhibiting the early steps of replication. IFITM3 is identified as interferon-induced cellular proteins that restrict infections by retroviruses and filoviruses and of influenza virus and flaviviruses, respectively. IFITM3, the most potent antiviral IFITM, was found to inhibit an uncharacterized early infectious event after VSV endocytosis, but before primary transcription of its viral genome. IFITM proteins are viral restriction factors that can inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. They differentially restrict the entry of a broad range of enveloped viruses, and modulate cellular tropism independently of viral receptor expression. This antibody recognizes both IFITM2 and IFITM3.
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