- ￥5800
- Proteintech
- 68194-1-PBS
- 2025年10月09日
- WB, IHC, IF/ICC, IP, Indirect ELISA
- Mouse
- Human, Mouse, Rat, Rabbit, Pig
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human NNT protein
- 亚型：
IgG2b
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse, Rat, Rabbit, Pig
- 宿主：
Mouse
- 应用范围：
WB, IHC, IF/ICC, IP, Indirect ELISA
- 靶点：
NNT
- 抗体英文名：
NNT Monoclonal antibody, PBS Only
- 抗体名：
NNT Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
68194-1-PBS targets NNT in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, Rabbit, Pig samples.
| 经测试应用 | WB, IHC, IF/ICC, IP, Indirect ELISA |
| 经测试反应性 | Human, Mouse, Rat, Rabbit, Pig |
| 免疫原 |
CatNo: Ag4259 Product name: Recombinant human NNT protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 30-236 aa of BC032370 Sequence: MNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLTEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | nicotinamide nucleotide transhydrogenase |
| 别名 | NNT |
| 计算分子量 | 1085 aa, 114 kDa |
| 观测分子量 | 114 kDa |
| GenBank蛋白编号 | BC032370 |
| 基因名称 | NNT |
| Gene ID (NCBI) | 23530 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q13423 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NNT(nicotinamide nucleotide transhydrogenase) is a transmembrane protein and functions as a proton pumping transhydrogenase. The protein is present in both prokaryotes and eukaryotes and is located in the inner membrane of mitochondria. In prokaryotic cells, the enzyme is composed of α and β subunits of 54 and 48 kDa, respectively. In eukaryotic cells, the enzyme is usually composed of a single peptide of 114 kDa. Although NNT catalyzes the interconversion of NADH and NADPH, the forward reaction using the reducing power of NADH to regenerate NADPH would be favored under conditions of oxidative stress(PMID:16497723). It can exsit as a homodimer(PMID:21882037).
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