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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG1, kappa
- 保存条件:
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
Cardinal Red™ Fluorescent Dye
- 适应物种:
Human
- 宿主:
Mouse
- 应用范围:
FC
- 靶点:
CD81
- 抗体英文名:
Cardinal Red™ Anti-Human CD81 (5A6)
- 抗体名:
Cardinal Red™ Anti-Human CD81 (5A6)
- 规格:
25tests/100tests
| 规格: | 25tests | 产品价格: | ¥960.0 |
|---|---|---|---|
| 规格: | 100tests | 产品价格: | ¥2410.0 |
经过测试的应用
| Positive FC detected in | human PBMCs |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in 100 μl suspension |
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CR-65195 targets CD81 in FC applications and shows reactivity with Human samples.
| 经测试应用 | FC |
| 经测试反应性 | Human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | CD81 molecule |
| 别名 | CD81, CD81 antigen, CD81 molecule, S5.7, TAPA1, Tetraspanin 28, Tspan 28, TSPAN28 |
| 计算分子量 | 26 kDa |
| GenBank蛋白编号 | BC002978 |
| 基因名称 | CD81 |
| Gene ID (NCBI) | 975 |
| ENSEMBL Gene ID | ENSG00000110651 |
| RRID | AB_3084976 |
| 偶联类型 | Cardinal Red™ Fluorescent Dye |
| 最大激发/发射波长 | 592 nm / 611 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P60033 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD81 (also known as TAPA1or TSPAN28) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Many of these members are expressed on leukocytes and have been implicated in signal transduction, cell-cell interactions, and cellular activation and development. CD81 is involved in signal transduction and cell adhesion in the immune system (PMID: 9597125). CD81 has also been identified as en essential receptor for HCV (hepatitis C virus) (PMID: 21428934).
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文献和实验CD81 分子 CD81 常用单克隆抗体或代号: ID6,5A6;(TAPA- 1) 主要表达细胞: 广泛,包括B,T,M [B] 分子质量(kDa)和结构: p26(TM4-SF) 功 能: 增殖抗体靶抗原,与CD19、CD21相连,组成B细胞复合体 CD81 Aka Target of an Anti-Proliferative Antibody (TAPA1)
三句话读懂一篇 CNS,鸟类迁移的秘密揭晓,绿色中药助力肥胖治疗,突破血脑屏障的递送技术...
humanization comes to the rescue of circulating human red blood cells。该工作将小鼠肝脏替换为人肝脏,发现人的红细胞在人源化小鼠体内正常生长发育,成熟的红细胞能够在小鼠体内循环,进而使得人的血液流淌。该新型人源化小鼠研究工具可用于造血干细胞疾病、红细胞和肝脏生理学联系研究,为临床药物的筛选鉴定开辟新途径。 图 1:来源 Science 2. Cell Metabolism: 高纤维膳食预防肥胖孕妇对后代认知及行为的伤害 动物和人体研究数据表明,孕妇
B 细胞的抗原识别结构辅助受体和辅佐分子 在成熟B细胞表面,CDl9、CD21与CD81以非共价键组成B细胞活化的辅助受体复合物(CO-receptor complex)。它们所起的作用类似于T细胞表面的辅助受体CD4或CD8。 (1)CD21:又称Ⅱ型补体受体(CR2),为单链工型跨膜糖蛋白,分子质量为145kDa,胞外区由15个短同源重复序列(SCR)组成。配体是补体C3的裂解片段C3dg、C3d和iC3b。CD21表达于成熟B细胞和FDC,部分T细胞和鼻咽癌上皮细胞也有表达
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