- ￥5800
- Proteintech
- 85627-1-PBS
- 2025年10月09日
- WB, IHC, Indirect ELISA
- Rabbit
- human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human HERPUD1 protein
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
WB, IHC, Indirect ELISA
- 靶点：
HERPUD1
- 抗体英文名：
HERPUD1 Recombinant monoclonal antibody, PBS Only
- 抗体名：
HERPUD1 Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
85627-1-PBS targets HERPUD1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IHC, Indirect ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag34891 Product name: Recombinant human HERPUD1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 94-391 aa of BC008320 Sequence: MPEINAKVAESTEEPAGSNRGQYPEDSSSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN* |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| 别名 | HERP, Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, KIAA0025, Methyl methanesulfonate, MIF1 |
| 计算分子量 | 44 kDa |
| 观测分子量 | 54 kDa |
| GenBank蛋白编号 | BC008320 |
| 基因名称 | HERPUD1 |
| Gene ID (NCBI) | 9709 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q15011 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1), also called HERP or MIF1, is component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. HERP is strongly induced by ER stress but rapidly degraded by proteasome. HERP interacts with members of the ubiquilin family, which function as a shuttle factor to deliver ubiquitinated substrates to the proteasome for degradation. HERP is present in activated microglia in senile plaques in the brain of patients with Alzheimer disease, and there is evidence suggesting HERP increase nigro-striatal dopaminergic activity and is able to improve symptoms in patients with Parkinson's disease, levodopa-related dyskinesias and Tardive dyskinesia. MW of HERP is 54 kDa (PMID: 23620059).
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