- ￥5800
- Proteintech
- 68437-1-PBS
- 2025年10月09日
- WB, Indirect ELISA
- Mouse
- Human, mouse, rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human HDAC5 protein
- 亚型：
IgG2b
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human, mouse, rat
- 宿主：
Mouse
- 应用范围：
WB, Indirect ELISA
- 靶点：
HDAC5
- 抗体英文名：
HDAC5 Monoclonal antibody, PBS Only
- 抗体名：
HDAC5 Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
68437-1-PBS targets HDAC5 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA |
| 经测试反应性 | Human, mouse, rat |
| 免疫原 |
CatNo: Ag30557 Product name: Recombinant human HDAC5 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 371-513 aa of NM_005474 Sequence: NISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVM |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | histone deacetylase 5 |
| 别名 | Antigen NY CO 9, FLJ90614, HD5, HDAC5, histone deacetylase 5, KIAA0600, NY CO 9 |
| 计算分子量 | 122 kDa |
| 观测分子量 | 140 kDa |
| GenBank蛋白编号 | NM_005474 |
| 基因名称 | HDAC5 |
| Gene ID (NCBI) | 10014 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9UQL6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Histone acetylation and deacetylation alternately exposes and occludes DNA to transcription factors. At least 4 classes of HDAC were identified. HDAC5 is a class II HDAC. HDAC5 responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC5 is involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, HDAC5 shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.
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