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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG1, kappa
- 保存条件:
Store at 2-8°C. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 宿主:
Mouse
- 应用范围:
FC
- 靶点:
CD71
- 抗体英文名:
Anti-Human CD71 (OKT9)
- 抗体名:
Anti-Human CD71 (OKT9)
- 规格:
100ug/500ug
| 规格: | 100ug | 产品价格: | ¥970.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥3020.0 |
经过测试的应用
| Positive FC detected in | PHA treated human PBMCs |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.2 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65235-1-Ig targets CD71 in WB, FC applications and shows reactivity with Human samples.
| 经测试应用 | FC |
| 文献引用应用 | WB |
| 经测试反应性 | Human |
| 文献引用反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | transferrin receptor (p90, CD71) |
| 别名 | CD71, p90, sTfR, T9, TFR, TFR1, TFRC, TR, Transferrin receptor protein 1, TRFR |
| 计算分子量 | 85 kDa |
| GenBank蛋白编号 | BC001188 |
| 基因名称 | CD71 |
| Gene ID (NCBI) | 7037 |
| ENSEMBL Gene ID | ENSG00000072274 |
| RRID | AB_2935134 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P02786 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.
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文献和实验| Species | Application | Title |
|---|---|---|
| mouse | WB | Metab Brain Dis Edaravone dextranol alleviates ferroptosis, Cuproptosis, and blood-brain barrier damage after acute cerebral infarctionAuthors - Guimin Jin |
CD71 分子 CD71 常用单克隆抗体或代号: OKT9;(TfR) 主要表达细胞: Mac,增殖细胞 [NL] 分子质量(kDa)和结构: p95(同源二聚体) 功 能:结合白细胞生长 CD71 Aka transferrin receptor Present on actively proliferating cells; essential for iron
网络 二、Ig超家族的特点 (一)Ig超家族的结构特点 Ig超家族成员均含有1~7个Ig样结构域,每个Ig样结构域约含70~110个氨基酸残基。其二级结构是两个各含3~5个反平行β折叠股所形成的β片层(anti-parallel β-pleated sheet)平面,每个反平行β折叠股由5~10个氨基酸残基组成,β
Purifying and Measuring Immunoglobulin E (IgE) and Anti-IgE
of enzyme-linked immunosorbent assays (ELISAs) and monoclonal antibody technology has proven instrumental for advancing the science of Ig biology. IgE is of interest as it is the primary Ig responsible for allergic reactions ranging from allergic rhinitis
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