- ￥3600 - 5000
- Proteintech
- 98070-1-PBS
- 2025年10月09日
- FC (Intra)
- Rabbit
- human
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- 详细信息
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
FC (Intra)
- 靶点：
Granzyme B
- 抗体英文名：
Anti-Human Granzyme B Rabbit Recombinant Antibody, PBS Only
- 抗体名：
Anti-Human Granzyme B Rabbit Recombinant Antibody, PBS Only
- 规格：
500ug/1mg
| 规格： | 500ug | 产品价格： | ￥3600.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥5000.0 |
产品信息
98070-1-PBS targets Granzyme B in FC (Intra) applications and shows reactivity with human samples.
| 经测试应用 | FC (Intra) |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Product name: Source: -derived, Tag: His Tag Domain: of Sequence: |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| 别名 | GZMB, 240761G4, Cathepsin G-like 1, CCPI, CGL 1 |
| 计算分子量 | 247 aa, 28 kDa |
| GenBank蛋白编号 | BC030195 |
| 基因名称 | Granzyme B |
| Gene ID (NCBI) | 3002 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P10144 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GZMB (Granzyme B) is also named as CGL1, CSPB, CTLA1, GRB and belongs to the Granzyme subfamily. This enzyme is necessary for target cell lysis in cell-mediated immune responses. The cytotoxic lymphocyte protease granzyme B can promote apoptosis through direct processing and activation of members of the caspase family. Granzyme B can also cleave the BH3-only protein, BID, to promote caspase-independent mitochondrial permeabilization (PMID:17283187). Granzyme B induces lamin B degradation in isolated nuclei less efficiently than Granzyme A (PMID:11331782).
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