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Anti-Human CD141/Thrombomoduli

n Rabbit Recombinant Antibody, PBS Only 98037-2-PBS
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  • ¥3600 - 5000
  • Proteintech已认证
  • 98037-2-PBS
  • 2025年10月09日
  • FC
  • Rabbit
  • human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      IgG

    • 保存条件

      Store at -80°C.

    • 克隆性

      Recombinant

    • 标记物

      Unconjugated

    • 适应物种

      human

    • 宿主

      Rabbit

    • 应用范围

      FC

    • 靶点

      CD141/Thrombomodulin

    • 抗体英文名

      Anti-Human CD141/Thrombomodulin Rabbit Recombinant Antibody, PBS Only

    • 抗体名

      Anti-Human CD141/Thrombomodulin Rabbit Recombinant Antibody, PBS Only

    • 规格

      500ug/1mg

    规格:500ug产品价格:¥3600.0
    规格:1mg产品价格:¥5000.0
    Planning an IHC experiment? We recommend our IHCeasy CD141/Thrombomodulin Ready-To-Use IHC Kit. CD141/Thrombomodulin primary antibody included.

    产品信息

    98037-2-PBS targets CD141/Thrombomodulin in FC applications and shows reactivity with human samples.

    经测试应用 FC
    经测试反应性 human
    免疫原

    fusion protein

    宿主/亚型 Rabbit / IgG
    抗体类别 Recombinant
    产品类型 Antibody
    全称 thrombomodulin
    别名 THBD, Thrombomodulin, THRM, Fetomodulin, CD141
    计算分子量60 kDa
    GenBank蛋白编号NM_000361.3
    基因名称 THBD
    Gene ID (NCBI) 7056
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein A purfication
    UNIPROT IDP07204
    储存缓冲液 PBS only, pH 7.3.
    储存条件Store at -80°C.
    The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

    背景介绍

    Thrombomodulin, also known as CD141, is an endothelial cell surface glycoprotein that forms a 1:1 complex with the coagulation factor thrombin and plays an important role as a natural anticoagulant. Thrombomodulin serves to convert thrombin from a procoagulant protein into the activator for protein C. Once converted to activated protein C (APC), this protein serves as a major anticoagulant in blood (PMID: 2827310). Thrombomodulin is also located in other cells (keratinocytes, osteoblasts, macrophages,...) where it might be involved in cell differentiation or in inflammation (PMID: 9814688). In humans, thrombomodulin is encoded by the THBD gene. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. Thrombomodulin is glycosylated and has an apparent molecular weight of 75 to 110 kDa (PMID: 1650405; 2827310).

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    图标文献和实验
    相关实验
    • Immunofluorescence: Rabbit Anti-Murine RELMα

      for 25 minutes. 3. Incubate the tissue section with blocking buffer for 20 minutes. 4. Incubate the tissue section overnight at 4?C with Rabbit Anti-Murine RELMα at 4.0 ng/mL in 1X PBS with 0.01% Triton-X and 0.5% BSA. Wash the slide

    • Anti-HA Immunocytology

      . A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600 of 0.75 to 1.

    • Anti-HA Immunocytology

      suspended in PBS. A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600

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