- ￥5800
- Proteintech
- 66830-1-PBS
- 2025年10月09日
- WB, IF/ICC, FC (Intra), ELISA
- Mouse
- human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human APOE protein
- 亚型：
IgG1
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Mouse
- 应用范围：
WB, IF/ICC, FC (Intra), ELISA
- 靶点：
APOE
- 抗体英文名：
APOE Monoclonal antibody, PBS Only
- 抗体名：
APOE Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
66830-1-PBS targets APOE in WB, IF/ICC, FC (Intra), ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IF/ICC, FC (Intra), ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag28186 Product name: Recombinant human APOE protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 66-317 aa of BC003557 Sequence: QEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | Apolipoprotein E |
| 别名 | 1B2C9, Apo E, Apo-E, apoe4, apolipoprotein E |
| 计算分子量 | 36 kDa |
| 观测分子量 | 34-36 kDa |
| GenBank蛋白编号 | BC003557 |
| 基因名称 | APOE |
| Gene ID (NCBI) | 348 |
| RRID | AB_2882173 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P02649 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The apolipoprotein E (APOE) is a 299-amino acid polypeptide that mediates the binding, internalization, and catabolism of lipoprotein particles, and also serve as a ligand for the LDL (APO B/E) receptor and for the specific APOE receptor (chylomicron remnant) of hepatic tissues. The very strong association of the APOE ɛ4 allele with AD risk and its role in the accumulation of amyloid β in brains of people and animal models solidify the biological relevance of APOE isoforms but do not provide mechanistic insight.
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