- ￥5800
- Proteintech
- 84425-5-PBS
- 2025年10月09日
- IHC, IF/ICC, Indirect ELISA
- Rabbit
- human, rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human C1orf170 protein
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human, rat
- 宿主：
Rabbit
- 应用范围：
IHC, IF/ICC, Indirect ELISA
- 靶点：
PERM1
- 抗体英文名：
PERM1 Recombinant monoclonal antibody, PBS Only
- 抗体名：
PERM1 Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
84425-5-PBS targets PERM1 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, rat samples.
| 经测试应用 | IHC, IF/ICC, Indirect ELISA |
| 经测试反应性 | human, rat |
| 免疫原 |
CatNo: Ag23833 Product name: Recombinant human C1orf170 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-58 aa of BC006300 Sequence: MCLVFVAFATWAVRTSDPHTPDAWKTALLANVGTISAIRYFRRQAGQGRRSHSPSPSS |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | chromosome 1 open reading frame 170 |
| 别名 | C1orf170, PERM, 241613B6 |
| GenBank蛋白编号 | BC006300 |
| 基因名称 | C1orf170 |
| Gene ID (NCBI) | 84808 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q5SV97 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PERM1 (PGC-1/ERR-induced regulator in muscle 1) is a muscle-specific protein induced by PGC-1α and ERRα. PERM1 protein expression is mainly restricted to heart and skeletal muscle, indicating PERM1 functions as a tissue-specific regulator of mitochondrial biogenesis in response to exercise (PMID: 33549681, 36028747). Ablation of Perm1 in mice results in reduced protein expression of lipin-1 accompanied by accumulation of specific phospholipid species (PMID: 33549681). There are two major isoforms of Perm1 protein, the short isoform is about 85 kDa, and the long isoform is 105 kDa.
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