- ￥5800
- Proteintech
- 68033-1-PBS
- 2025年10月09日
- IHC, IF-P, Indirect ELISA
- Mouse
- human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human CR1 protein
- 亚型：
IgG1
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Mouse
- 应用范围：
IHC, IF-P, Indirect ELISA
- 靶点：
CD35
- 抗体英文名：
CD35 Monoclonal antibody, PBS Only
- 抗体名：
CD35 Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
68033-1-PBS targets CD35 in IHC, IF-P, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IHC, IF-P, Indirect ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag30268 Product name: Recombinant human CR1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1740-1971 aa of NM_000573 Sequence: DEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHD |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | complement component (3b/4b) receptor 1 (Knops blood group) |
| 别名 | C3b/C4b receptor, C3BR, Complement receptor type 1, CR1, KN |
| 计算分子量 | 224 kDa |
| GenBank蛋白编号 | NM_000573 |
| 基因名称 | CR1 |
| Gene ID (NCBI) | 1378 |
| ENSEMBL Gene ID | ENSG00000203710 |
| RRID | AB_2918775 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P17927 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD35, also known as complement receptor type 1 (CR1) or C3b/C4b receptor, is a single-chain glycoprotein consisting of 30 repeating homologous protein domains known as short consensus repeats (~60 amino acids each) followed by transmembrane and cytoplasmic domains (PMID: 8765013). CD35 is variably expressed by granulocytes, monocytes, B cells, some T cells, erythrocytes, follicular dendritic cells, Langerhans cells, and glomerular podocytes (PMID: 19004497). CD35 acts as a receptor for C3b and C4b and plays important roles in the regulation of the complement cascade and clearance of immune complexes. A soluble form of CD35 has been found in plasma (PMID: 3156931). It has been reported that soluble CD35 is produced by a proteolytic cleavage in the C-terminal region of CD35 transmembrane domain (PMID: 9405292).
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