- ￥480 - 950
- Proteintech
- CLV510-98115
- 2025年10月09日
- FC
- Rabbit
- human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Recombinant
- 标记物：
CoraLux Violet 510 Fluorescent Dye
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
FC
- 靶点：
TIM3
- 抗体英文名：
CoraLux Violet 510 Anti-Human TIM3 Rabbit Recombinant Antibody
- 抗体名：
CoraLux Violet 510 Anti-Human TIM3 Rabbit Recombinant Antibody
- 规格：
25tests/100tests
| 规格： | 25tests | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100tests | 产品价格： | ￥950.0 |
经过测试的应用
| Positive FC detected in | Anti-CD3/CD28 treated human PBMCs |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in a 100 µl suspension |
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CLV510-98115 targets TIM3 in FC applications and shows reactivity with human samples.
| 经测试应用 | FC |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | hepatitis A virus cellular receptor 2 |
| 别名 | 241422H1, CD366, HAVCR2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3 |
| 计算分子量 | 301 aa, 33 kDa |
| GenBank蛋白编号 | BC020843 |
| 基因名称 | TIM3 |
| Gene ID (NCBI) | 84868 |
| 偶联类型 | CoraLux Violet 510 Fluorescent Dye |
| 最大激发/发射波长 | 410 nm / 501 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q8TDQ0 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
TIM3, also known as HAVCR2, is a member of the recently discovered T cell Ig and mucin domain-containing molecule superfamily. TIM3 is a negative regulatory molecule that is important for T cell tolerance and has a crucial role in autoimmunity and T cell exhaustion during chronic viral infection (PMID: 23180819). TIM3 is expressed by T-helper type 1 (Th1) cells, macrophage, monocyte, dendritic cells, CD8+ T cell and other lymphocyte subsets. Galectin-9 is a ligand for TIM3. TIM3-galectin-9 pathway negatively regulates T helper type 1 immunity (PMID: 16286920).
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The Mouse as Model System to Study Host‐Pathogen Interactions in Influenza A Infections
) Primary antibody (polyclonal, against influenza A virions, H1N1; Virostat, http://www.virostat‐inc.com/) Secondary antibody (anti‐goat‐IgG‐HRP; KPL, http://www.kpl.com
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