- ￥5800
- Proteintech
- 84640-1-PBS
- 2025年10月09日
- WB, Indirect ELISA
- Rabbit
- human
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- 详细信息
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
WB, Indirect ELISA
- 靶点：
SPHK1
- 抗体英文名：
SPHK1 Recombinant monoclonal antibody, PBS Only
- 抗体名：
SPHK1 Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
84640-1-PBS targets SPHK1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | sphingosine kinase 1 |
| 别名 | 241017A6, Acetyltransferase SPHK1, EC:2.3.1.-, EC:2.7.1.91, SK1 |
| 计算分子量 | 51 kDa |
| 观测分子量 | 42 kDa |
| GenBank蛋白编号 | NM_182965 |
| 基因名称 | SPHK1 |
| Gene ID (NCBI) | 8877 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q9NYA1 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SPHK(Sphingosine kinase 1) is also named as SPHK, SPK.It catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions and is precariously perched at the balance point between progrowth and pro-death signalling in the cell.Endogenous SPHK1 purified from placenta has identical enzymatic characteristics, suggesting posttranslational modification does not effect functional properties(PMID:10947957).It has 2 isoforms produced by alternative splicing and can form the oligomeric structure(PMID:22335554).
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